decoupler.get_ksn_omnipath

decoupler.get_ksn_omnipath(license='academic')

OmniPath kinase-substrate network

Wrapper to access the OmniPath kinase-substrate network. It contains a collection of kinases and their target phosphosites. Each interaction is is weighted by its mode of regulation (either positive for phosphorylation or negative for dephosphorylation).

Parameters:

license: str

Which license to use, available options are: academic, commercial, or nonprofit. By default, is set to academic to retrieve all possible interactions.

Returns:

ksnDataFrame

Dataframe in long format containing target phosphosites for each kinase with their associated weights.